Compound Profiles

These are not recommendations

This is harm reduction information, not medical advice. All compounds carry risk. Even “High Risk” means significant health risk compared to not using. Get blood work done.

High RiskExtreme RiskNever Use

Injectables

Primobolan (Methenolone)

High Risk

Primo, Primo E, Methenolone Enanthate, Methenolone Acetate

Considered one of the mildest injectable steroids. Promotes slow, lean gains with minimal water retention. Expensive and commonly counterfeited, so gear testing is essential.

Half-life: Injectable (Enanthate): ~10 days. Oral (Acetate): ~5 hours.

Sustanon

High Risk

Sust, Sus 250

A pharmaceutical blend of four testosterone esters (Propionate 30mg, Phenylpropionate 60mg, Isocaproate 60mg, Decanoate 100mg). Commonly prescribed for TRT in the UK and Europe.

Half-life: ~15-18 days (driven by the decanoate ester)

Testosterone Propionate

High Risk

Test Prop, Test P

A short-ester testosterone requiring frequent injection (every other day). Provides rapid onset and clearance, making side effect management easier but injection frequency higher.

Half-life: ~2-3 days

Testosterone Cypionate

High Risk

Test Cyp, Test C

A long-ester testosterone very similar to enanthate. Most popular in the US for TRT. Provides stable blood levels with once or twice weekly injections.

Half-life: ~8-12 days

Testosterone Enanthate

High Risk

Test E

The most commonly used testosterone ester for steroid cycles. Provides stable blood levels with once or twice weekly injections. The standard recommendation for a first cycle in harm reduction communities.

Half-life: ~5-7 days

Testosterone Decanoate

High Risk

Test D, Test Deca

A very long-ester testosterone, most commonly found as a component of the Sustanon blend. Rarely used as a standalone ester. Extended half-life means very slow onset and clearance.

Half-life: ~15 days

Masteron Propionate

High Risk

Mast Prop, Mast P

The short-ester form of Masteron (drostanolone). Requires frequent injection. Provides a hardening, drying effect and mild anti-oestrogenic properties. Strongly accelerates hair loss.

Half-life: ~2-3 days

Masteron Enanthate

High Risk

Mast E

The long-ester form of Masteron (drostanolone). Less frequent injections but otherwise identical effects to Masteron Propionate. Same strong hair loss risk.

Half-life: ~5-7 days

Testosterone Undecanoate

High Risk

Nebido, Aveed, Test U

Ultra-long acting testosterone ester used in NHS TRT prescriptions. Injected every 10-14 weeks. Same base compound as all testosterone esters.

Half-life: ~20-21 days (terminal half-life much longer due to depot effect)

Drostanolone

High Risk

Masteron base, Drostanolone base

The parent compound of Masteron (drostanolone propionate and enanthate). A DHT-derivative with anti-estrogenic properties and moderate anabolic effects.

Half-life: Propionate: ~2-3 days. Enanthate: ~7-10 days

Nandrolone Phenylpropionate (NPP)

Extreme Risk

NPP, Nandrolone Phenylprop

The short-ester form of nandrolone. Faster acting than Deca Durabolin with quicker clearance, making side effects easier to manage. Still carries the same 19-nor risks.

Half-life: ~2-3 days

Nandrolone Decanoate (Deca Durabolin)

Extreme Risk

Deca, Deca Durabolin

The long-ester form of nandrolone, commonly known as 'Deca'. One of the oldest and most widely used injectables. Known for steady gains and joint benefits, but with very long clearance and difficult PCT recovery.

Half-life: ~6-12 days

Clostebol

Extreme Risk

Chlorotestosterone, Megagrisevit, Steranabol

A mild anabolic steroid used in some countries as a topical medication for wound healing. Occasionally appears in contaminated supplements or creams. Famous for causing inadvertent doping violations.

Half-life: ~8-12 hours (oral); varies by preparation

Stanozolol Depot

Extreme Risk

Winstrol Depot, Injectable Winstrol, Injectable Stanozolol

The injectable form of Winstrol (stanozolol). A water-based suspension that is notorious for painful injections. Still liver-toxic despite being injectable.

Half-life: ~24 hours

Injectable Anavar

Extreme Risk

Injectable Oxandrolone

An injectable preparation of oxandrolone (Anavar). Not a pharmaceutical product — made by underground labs to bypass first-pass liver metabolism.

Half-life: ~9-12 hours

Boldenone (Equipoise)

Never Use

EQ, Bold, Boldenone Undecylenate, Equipoise

Originally developed as a veterinary compound for horses. A slow-acting injectable known for increasing appetite, vascularity, and red blood cell production. The haematocrit increase is the primary safety concern.

Half-life: ~14 days

Trenbolone Acetate

Never Use

Tren Ace, Tren A

The short-ester form of trenbolone and the most commonly used variant. Requires frequent injection but clears the body faster if side effects become unmanageable.

Half-life: ~1-2 days

Trenbolone Enanthate

Never Use

Tren E

The long-ester form of trenbolone. Less frequent injections but side effects take much longer to resolve once they appear, making it harder to manage than the acetate form.

Half-life: ~5-7 days

DHB (Dihydroboldenone)

Never Use

Dihydroboldenone, 1-Testosterone

The 5-alpha reduced form of boldenone. A very potent injectable known for producing lean, dry gains but also notorious for severe post-injection pain (PIP).

Half-life: Varies by ester

Trestolone (MENT)

Never Use

MENT, Trestolone Acetate

An extremely potent 19-nor injectable, estimated at roughly 10 times more potent than testosterone. Very limited safety data. Rapid onset of effects and side effects due to short ester.

Half-life: ~8-12 hours (acetate ester)

Trenbolone Hexahydrobenzylcarbonate

Never Use

Parabolan, Tren Hex

The original pharmaceutical-grade trenbolone ester. Intermediate duration between acetate and enanthate. Carries all the extreme risks of trenbolone.

Half-life: ~14 days

Orals

Anavar (Oxandrolone)

High Risk

Var, Oxandrolone

Often considered one of the 'milder' oral steroids. Popular among beginners and women. Still carries real risks, particularly to cholesterol and liver values.

Half-life: ~9 hours

Proviron (Mesterolone)

High Risk

Mesterolone

A mild oral DHT derivative used primarily as an ancillary compound. Improves free testosterone levels by binding to SHBG. Not a significant mass builder but used for its complementary effects.

Half-life: ~12 hours

Dianabol (Methandrostenolone)

Extreme Risk

Dbol, Methandrostenolone, Diana

One of the oldest and most popular oral steroids. Known for rapid mass and strength gains, but with significant water retention and liver strain.

Half-life: ~3–5 hours

Winstrol (Stanozolol)

Extreme Risk

Winny, Stanozolol

A DHT-derivative oral steroid known for a dry, hard look. Highly hepatotoxic and particularly harsh on joints, drying out synovial fluid and increasing tendon injury risk.

Half-life: ~9 hours

Anadrol (Oxymetholone)

Extreme Risk

Drol, A-bombs, Oxy, Oxymetholone

One of the most powerful oral steroids available. Produces rapid, dramatic mass and strength gains, but is extremely hepatotoxic and causes severe oestrogen-related side effects. Not suitable for beginners.

Half-life: ~8-9 hours

Turinabol (Chlorodehydromethyltestosterone)

Extreme Risk

Tbol, OT, Oral Turinabol

A derivative of Dianabol modified to reduce oestrogenic activity. Produces slow, lean gains without water retention. Often presented as 'safe' but still carries all the risks of oral steroid use.

Half-life: ~16 hours

Epistane

Extreme Risk

Epi, Havoc, Epithio

A designer steroid with mild anti-oestrogenic properties. Originally sold as a 'prohormone' supplement. Hepatotoxic. Produces moderate lean gains with a dry look.

Half-life: ~6 hours

Dimethazine

Extreme Risk

DMZ, Dymethazine, Mebolazine

A designer steroid consisting of two superdrol molecules bonded together. Extremely liver-toxic with potent anabolic effects. Now a controlled substance in many jurisdictions.

Half-life: ~10-16 hours

Methylstenbolone

Extreme Risk

M-Sten, Ultradrol, 2,17a-dimethyl-5a-androsta-1-en-17b-ol-3-one

A designer oral steroid related to Superdrol. Produces dry, lean gains with significant liver toxicity. Previously sold as a legal prohormone.

Half-life: ~6-8 hours

Desoxymethyltestosterone

Extreme Risk

DMT, Madol, Pheraplex

A designer steroid that was undetectable by standard drug tests until 2005. Created specifically to evade testing. Now a Schedule III controlled substance.

Half-life: Unknown — estimated 6-10 hours

Halotest

Extreme Risk

Fluoxymesterone generic, Halo

See Halotestin entry. A generic/UGL name for fluoxymesterone. One of the most androgenic oral steroids available.

Half-life: ~6-9 hours

Tbol

Extreme Risk

Oral Turinabol, 4-Chlorodehydromethyltestosterone

See Turinabol entry. A common abbreviation for oral Turinabol. The East German state-sponsored doping compound.

Half-life: ~16 hours

Superdrol (Methyldrostanolone)

Never Use

SD, Methyl-drostanolone

An extremely potent oral steroid considered by many to be the single most liver-toxic oral steroid available. Can cause severe lethargy, jaundice, and liver injury even at moderate doses.

Half-life: ~8-9 hours

Halotestin (Fluoxymesterone)

Never Use

Halo, Fluoxymesterone

One of the most potent and liver-toxic oral steroids in existence. Used almost exclusively for aggression and strength in powerlifting and combat sports. Not a mass builder. Extreme hepatotoxicity.

Half-life: ~6-8 hours

Mibolerone

Never Use

Cheque Drops

An extremely potent oral androgen originally developed as a veterinary drug to prevent oestrus in dogs. Used pre-competition for aggression. One of the most hepatotoxic steroids in existence.

Half-life: ~4 hours

Methyltrenbolone

Never Use

Metribolone, Oral Trenbolone, Oral Tren, M-Tren

An extremely potent oral anabolic steroid. One of the most liver-toxic compounds in existence. Used in research settings to study androgen receptors due to its extreme binding affinity.

Half-life: ~6-8 hours

Tetrahydrogestrinone

Never Use

THG, The Clear

The infamous 'Clear' from the BALCO scandal. A designer steroid created specifically to be undetectable. Never approved for any use and carries unknown risks.

Half-life: Unknown

Oral Methyltrienolone

Never Use

Oral Tren, M-Tren Tabs

Oral tablet form of methyltrenbolone. See methyltrenbolone entry. One of the most liver-toxic compounds in existence.

Half-life: ~6-8 hours

Peptides

GHK-Cu

High Risk

GHK Copper

A naturally occurring copper peptide involved in skin and tissue repair. Used for wound healing, anti-ageing, and recovery. Generally considered lower risk than most peptides but still lacks clinical data for performance use.

Half-life: Unknown (limited pharmacokinetic data)

NAD+

High Risk

Nicotinamide Adenine Dinucleotide

A coenzyme found in all living cells, essential for energy metabolism. Used for energy, anti-ageing, and recovery. Available as IV infusions, injections, and oral supplements.

Half-life: Varies by route of administration

BPC-157

Extreme Risk

Body Protection Compound

A synthetic peptide derived from a protein found in gastric juice. Widely used for tendon, ligament, and gut healing. No human clinical trials have been completed.

Half-life: ~4 hours

TB-500

Extreme Risk

Thymosin Beta-4

A synthetic version of Thymosin Beta-4, a naturally occurring peptide involved in tissue repair and recovery. Used for injury healing. Limited human safety data.

Half-life: Unknown (limited pharmacokinetic data in humans)

Ipamorelin

Extreme Risk

A selective growth hormone releasing peptide (GHRP) with minimal impact on cortisol and prolactin. Considered the 'cleanest' GHRP. Often paired with CJC-1295 for synergistic GH release.

Half-life: ~2 hours

CJC-1295 / Mod GRF 1-29

Extreme Risk

CJC-1295 no DAC, Modified GRF(1-29), ModGRF

A growth hormone releasing hormone (GHRH) analogue. Amplifies natural GH pulses when paired with a GHRP like Ipamorelin. The 'no DAC' version is preferred for pulsatile release. Not approved for human use.

Half-life: ~30 minutes (without DAC), ~8 days (with DAC)

GHRP-2

Extreme Risk

Pralmorelin

A potent growth hormone releasing peptide. Produces strong GH pulses but also raises cortisol and prolactin more than Ipamorelin. Causes moderate hunger. Not approved for human use.

Half-life: ~1-2 hours

GHRP-6

Extreme Risk

A growth hormone releasing peptide that causes intense hunger. Strong GH release but raises cortisol, prolactin, and ghrelin significantly. Often used during bulking. Not approved for human use.

Half-life: ~2-3 hours

PT-141 (Bremelanotide)

Extreme Risk

Bremelanotide, Vyleesi

A melanocortin receptor agonist used for sexual dysfunction. Works via the central nervous system, not blood flow like Viagra. Can cause significant nausea. Approved for female hypoactive sexual desire disorder in the US.

Half-life: ~2.5 hours

AOD-9604

Extreme Risk

Anti-Obesity Drug 9604

A modified fragment of human growth hormone (amino acids 177-191). Marketed for fat loss without the typical side effects of full HGH. Limited human evidence. Not approved for human use as an injectable.

Half-life: ~2-3 hours (estimated)

Sermorelin

Extreme Risk

GRF(1-29), Geref

The first GHRH analogue developed. Stimulates natural growth hormone release. Shorter half-life than CJC-1295. Used in anti-aging clinics and as an alternative to exogenous HGH.

Half-life: ~10-20 minutes

Tesamorelin

Extreme Risk

Egrifta

A GHRH analogue approved for HIV-associated lipodystrophy. Used off-label for fat loss and GH elevation. One of the few GH peptides with clinical trial data in humans.

Half-life: ~26 minutes

Hexarelin

Extreme Risk

Examorelin

The most potent GHRP. Produces the strongest GH pulse but causes rapid desensitisation, making it impractical for long-term use. Also raises cortisol and prolactin significantly.

Half-life: ~1-2 hours

Kisspeptin

Extreme Risk

Kisspeptin-10, Kisspeptin-54

A neuropeptide that stimulates GnRH release, triggering LH and FSH production. Being explored as a potential PCT agent and fertility treatment. Very early-stage research.

Half-life: ~28 minutes (Kisspeptin-54), ~4 minutes (Kisspeptin-10)

DSIP

Extreme Risk

Delta Sleep-Inducing Peptide

A neuropeptide claimed to improve deep sleep quality. Popular among users of compounds that disrupt sleep (especially Trenbolone). Very limited human data.

Half-life: ~15-25 minutes (but effects last hours)

Epithalon

Extreme Risk

Epitalon, Epithalone

A synthetic tetrapeptide claimed to activate telomerase, the enzyme that maintains telomere length. Used in anti-aging contexts. Very limited human data from Russian studies.

Half-life: ~10-15 minutes

Selank

Extreme Risk

A synthetic analogue of tuftsin with anxiolytic and nootropic properties. Used for anxiety reduction and cognitive enhancement. Approved in Russia but not elsewhere.

Half-life: ~10-15 minutes (but effects last hours)

Semax

Extreme Risk

A synthetic ACTH(4-10) analogue with nootropic and neuroprotective properties. Used for cognitive enhancement. Approved in Russia and Ukraine but not elsewhere.

Half-life: ~20 minutes (but effects last hours)

HGH Fragment 176-191

Extreme Risk

Frag 176-191, HGH Frag, AOD-9604 predecessor

A modified fragment of the growth hormone molecule (amino acids 176-191) that specifically targets fat loss without the growth-promoting effects of full HGH.

Half-life: ~15-20 minutes

LL-37

Extreme Risk

Cathelicidin, Human Cathelicidin

A naturally occurring antimicrobial peptide in the human immune system. Used experimentally for wound healing and immune support. No approved therapeutic use.

Half-life: ~4-6 hours

MOTS-c

Extreme Risk

Mitochondrial ORF of the 12S rRNA Type-C

A mitochondria-derived peptide that regulates metabolic homeostasis. Being studied for its effects on exercise capacity, fat metabolism, and insulin sensitivity.

Half-life: Unknown — estimated several hours

Follistatin

Extreme Risk

Follistatin-344, FS-344, Follistatin-315

A naturally occurring protein that inhibits myostatin, the protein responsible for limiting muscle growth. Highly experimental with significant theoretical risks.

Half-life: ~2-4 hours

Thymosin Alpha-1

Extreme Risk

TA1, Zadaxin

An immune-modulating peptide naturally produced by the thymus gland. Approved in some countries for hepatitis B/C treatment. Used off-label for immune support.

Half-life: ~2 hours

SS-31

Extreme Risk

Elamipretide, Bendavia, MTP-131

A mitochondria-targeted peptide in clinical trials for heart failure and mitochondrial diseases. Used experimentally for anti-ageing and exercise performance.

Half-life: ~4 hours

Dihexa

Extreme Risk

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

An experimental nootropic peptide claimed to be millions of times more potent than BDNF. Used in the biohacking community for cognitive enhancement. Extremely limited research.

Half-life: Unknown

Cerebrolysin

Extreme Risk

A mixture of brain-derived neurotrophic peptides used in some countries for neurological conditions. Used in the biohacking community for cognitive enhancement.

Half-life: ~12-24 hours (biological effect duration)

IGF-1 DES

Extreme Risk

IGF-1 DES(1-3), Des(1-3) IGF-1

A truncated version of IGF-1 that is 10 times more potent than regular IGF-1. Does not bind to IGF binding proteins, making it more bioavailable and more dangerous.

Half-life: ~20-30 minutes

MGF

Extreme Risk

Mechano Growth Factor, PEG-MGF, IGF-1Ec

A splice variant of IGF-1 released in response to muscle damage. The PEGylated version has an extended half-life. Used for localised muscle growth and recovery.

Half-life: MGF: ~5-7 minutes. PEG-MGF: ~several hours

GHK

Extreme Risk

GHK tripeptide, Glycyl-L-histidyl-L-lysine

A naturally occurring tripeptide involved in wound healing and tissue remodelling. The non-copper-bound form. Used for skin rejuvenation and general anti-ageing.

Half-life: ~30 minutes to 1 hour

IGF-1 LR3

Never Use

IGF-1 LR3, Long R3 IGF-1

A modified version of Insulin-like Growth Factor 1 with a longer half-life. Promotes muscle growth but also organ growth. Carries significant risks including hypoglycaemia and potential tumour promotion.

Half-life: ~20-30 hours

ACE-031

Never Use

Myostatin Inhibitor, ACVR2B-Fc

An experimental myostatin inhibitor originally developed for muscular dystrophy. Clinical trials were halted due to serious safety concerns including nosebleeds and gum bleeding.

Half-life: ~10-14 days

Weight Loss

Tirzepatide

High Risk

Mounjaro, Remedium

A dual GLP-1/GIP receptor agonist originally developed for type 2 diabetes. Produces dramatic weight loss. Now widely used off-label and through grey market sources for body composition.

Half-life: ~5 days

T4 (Levothyroxine)

High Risk

Levothyroxine, Synthroid

The thyroid hormone precursor that converts to T3 in the body. Less potent than direct T3 supplementation for fat loss. Used in the fitness community as a milder alternative, though still carries thyroid suppression risk.

Half-life: ~6-7 days

Yohimbine

High Risk

Yohimbe

An alpha-2 adrenergic receptor antagonist derived from tree bark. Used for mild fat loss, particularly targeting stubborn fat areas. Can cause significant anxiety and blood pressure spikes.

Half-life: ~0.5-2 hours

Semaglutide

High Risk

Ozempic, Wegovy, Rybelsus

A GLP-1 receptor agonist approved for type 2 diabetes (Ozempic) and obesity (Wegovy). Causes significant appetite suppression and weight loss. Widely sourced from grey market in the UK.

Half-life: ~7 days

Liraglutide

High Risk

Saxenda, Victoza

A GLP-1 receptor agonist approved for diabetes (Victoza) and weight management (Saxenda). Same drug class as semaglutide but requires daily injection and produces less weight loss.

Half-life: ~13 hours

L-Carnitine (Injectable)

High Risk

LCAR, Levocarnitine

Injectable form of L-Carnitine used for enhanced fat oxidation. Much higher bioavailability than oral. Increasingly popular in bodybuilding for cutting phases. Generally well-tolerated.

Half-life: ~2-3 hours (plasma)

Orlistat

High Risk

Xenical, Alli

A fat absorption inhibitor available over the counter (Alli) and by prescription (Xenical). Prevents roughly 30% of dietary fat from being absorbed.

Half-life: ~1-2 hours

Albuterol

High Risk

Salbutamol, Ventolin, ProAir

A beta-2 agonist bronchodilator used for asthma. Used off-label as a milder alternative to clenbuterol for fat loss and anti-catabolic effects.

Half-life: ~4-6 hours

Clenbuterol

Extreme Risk

Clen

Not a steroid. A beta-2 agonist originally developed as a bronchodilator. Used as a fat burner. Causes cardiac arrhythmias and has a narrow margin between effective and dangerous doses. Multiple deaths have been associated with overdose.

Half-life: ~36 hours

T3 (Liothyronine)

Extreme Risk

Cytomel, Liothyronine, T3 Cytomel

The active thyroid hormone. Burns fat by increasing metabolic rate but can permanently suppress thyroid function with prolonged use. Also causes significant muscle loss if used without anabolic support.

Half-life: ~2.5 days

Ephedrine

Extreme Risk

Ephedrine HCl, ECA Stack

A sympathomimetic amine used in ECA stacks (Ephedrine/Caffeine/Aspirin) for fat loss. Raises metabolic rate and suppresses appetite. Cardiovascular stimulant with abuse potential. Controlled in the UK.

Half-life: ~3-6 hours

Phendimetrazine

Extreme Risk

Bontril, Plegine

A prescription appetite suppressant and stimulant. Used for short-term weight management. Carries addiction potential and cardiovascular risks.

Half-life: ~2-4 hours (active metabolite: ~6-12 hours)

Phentermine

Extreme Risk

Adipex-P, Duromine, Suprenza

The most commonly prescribed appetite suppressant worldwide. A sympathomimetic amine related to amphetamine. Used for short-term weight management with cardiovascular risks.

Half-life: ~19-24 hours

Retatrutide

Never Use

Reta, APEX

An experimental triple agonist (GLP-1/GIP/glucagon receptor). Even more potent weight loss than tirzepatide in early trials, but with very limited safety data. Not approved for any use.

Half-life: ~5-6 days

DNP (2,4-Dinitrophenol)

Never Use

2,4-Dinitrophenol, Dinitrophenol

An industrial chemical that causes rapid fat loss by uncoupling mitochondrial oxidative phosphorylation. Has killed people in the UK. There is no safe dose. There is no antidote.

Half-life: ~36 hours (accumulates with repeated dosing)

Sibutramine

Never Use

Reductil, Meridia

A withdrawn appetite suppressant previously prescribed for obesity. Removed from the market worldwide due to increased cardiovascular events. Still found in contaminated supplements.

Half-life: ~1 hour (active metabolites: ~14-16 hours)

2,4-Dinitrophenol (DNP) — see DNP entry

Never Use

DNP

See the DNP entry. Listed here as a cross-reference. DNP is an industrial chemical with an extremely narrow margin between an effective dose and a lethal dose.

Half-life: ~36 hours (this long half-life is what makes it so dangerous — doses accumulate)

AI / PCT

HCG (Human Chorionic Gonadotropin)

High Risk

Pregnyl, Ovitrelle

A hormone that mimics LH (luteinising hormone) to maintain testicular function during steroid cycles. Used on-cycle to prevent testicular atrophy and during PCT to kickstart recovery.

Half-life: ~24-36 hours

Aromasin (Exemestane)

High Risk

Exemestane

A suicidal (irreversible) aromatase inhibitor. Permanently deactivates aromatase enzymes, meaning oestrogen levels only recover as the body produces new enzymes. Preferred by many over Arimidex for its lipid-friendly profile.

Half-life: ~24 hours

Arimidex (Anastrozole)

High Risk

Anastrozole

The most commonly used non-suicidal aromatase inhibitor. Temporarily blocks the aromatase enzyme. Can crash oestrogen if overdosed, and oestrogen can rebound when discontinued.

Half-life: ~40-50 hours

Nolvadex (Tamoxifen)

High Risk

Tamoxifen

The standard SERM used for PCT. Blocks oestrogen at the receptor in breast tissue while stimulating the HPTA to restart natural testosterone production. The cornerstone of most PCT protocols.

Half-life: ~5-7 days

Clomid (Clomiphene)

High Risk

Clomiphene, Clomiphene Citrate

A SERM used in PCT to stimulate LH and FSH production. More potent at stimulating the HPTA than Nolvadex but carries more side effects, particularly vision disturbances and emotional changes.

Half-life: ~5-7 days

Raloxifene

High Risk

Evista

A SERM used specifically for gynecomastia prevention and reversal. More targeted at breast tissue oestrogen receptors than Nolvadex. Less commonly used for general PCT.

Half-life: ~27 hours

HMG (Human Menopausal Gonadotropin)

High Risk

Menopur

A hormone preparation containing both LH and FSH. Used to restore fertility after steroid use. More targeted at fertility recovery than HCG alone, which only provides LH-like activity.

Half-life: ~24 hours

Letrozole

High Risk

Femara, Letro

The most potent aromatase inhibitor. Can reduce oestrogen to undetectable levels. Used for gynecomastia reversal and as an emergency AI. Crashing oestrogen is dangerous — use with caution.

Half-life: ~2-4 days

Cabergoline

High Risk

Dostinex, Caber

A dopamine agonist used to lower prolactin. Essential when running 19-nor compounds (Trenbolone, Nandrolone) that elevate prolactin. Can cause impulse control issues at higher doses.

Half-life: ~63-69 hours

Enclomiphene

High Risk

Androxal

The active trans-isomer of Clomiphene (Clomid). Stimulates LH and FSH without the oestrogenic side effects of Clomid's zuclomiphene isomer. Increasingly popular for PCT and testosterone optimisation.

Half-life: ~10 hours

Gonadorelin

High Risk

GnRH, Factrel, Lutrelef

Synthetic GnRH used to stimulate LH and FSH. Sometimes used as an alternative to HCG in TRT protocols to maintain testicular function. Requires frequent dosing.

Half-life: ~10-40 minutes

Toremifene

High Risk

Fareston

A SERM similar to Nolvadex (Tamoxifen). Used in PCT and gynecomastia prevention. May have a better side effect profile than Tamoxifen in some users.

Half-life: ~5 days

PCT Protocol Guide

High Risk

Post Cycle Therapy, PCT

Post-cycle therapy is a protocol used after an anabolic steroid cycle to restore natural testosterone production. Not a single compound but a structured approach using multiple drugs.

Half-life: N/A — protocol, not a single compound

Pramipexole

Extreme Risk

Mirapex, Prami

A dopamine agonist alternative to Cabergoline for prolactin control. Cheaper but causes significantly more nausea. Same impulse control disorder risks as Cabergoline.

Half-life: ~8-12 hours

On Cycle Support

Metformin

High Risk

Glucophage

An insulin sensitiser originally developed for type 2 diabetes. Used in bodybuilding to counter insulin resistance caused by HGH and other compounds. Can cause significant gastrointestinal side effects.

Half-life: ~6 hours

TUDCA

High Risk

Tauroursodeoxycholic Acid

The gold standard liver support supplement for oral steroid users. Significantly more effective than NAC alone at protecting against drug-induced liver injury. Essential with hepatotoxic orals.

Half-life: ~3-5 hours

NAC

High Risk

N-Acetyl Cysteine

A precursor to glutathione, the body's primary antioxidant. Commonly used for liver support on cycle. Less effective than TUDCA for cholestatic liver damage but provides broader antioxidant protection.

Half-life: ~5.6 hours

Telmisartan

High Risk

Micardis

An angiotensin receptor blocker (ARB) used for blood pressure management on cycle. Preferred by many over other BP medications due to additional PPARdelta-activating metabolic benefits.

Half-life: ~24 hours

Nebivolol

High Risk

Bystolic

A beta-blocker with additional nitric oxide-potentiating effects. Preferred for blood pressure management on cycle because it causes less exercise impairment than other beta-blockers.

Half-life: ~12-19 hours

Finasteride

High Risk

Propecia, Proscar

A 5-alpha reductase inhibitor used to prevent hair loss during steroid use. Blocks the conversion of testosterone to DHT. Can cause sexual side effects that persist after discontinuation in rare cases.

Half-life: ~5-6 hours (but DHT suppression lasts ~24 hours)

Tadalafil

High Risk

Cialis

A long-acting PDE5 inhibitor used for erectile dysfunction and daily blood pressure support. Used by the majority of steroid users. Also provides a mild blood pressure reduction and improved pumps.

Half-life: ~17.5 hours

Sildenafil

High Risk

Viagra

A PDE5 inhibitor used for erectile dysfunction. Shorter-acting than Tadalafil. Also used pre-workout for enhanced pumps. Same drug interactions and warnings as Tadalafil.

Half-life: ~3-5 hours

P5P

High Risk

Pyridoxal-5-Phosphate, Active Vitamin B6

The active form of Vitamin B6. Used as a first-line, mild prolactin reducer before resorting to Cabergoline. Generally safe at recommended doses.

Half-life: ~15-20 days (stored in tissue)

Taurine

High Risk

An amino acid used to manage painful muscle pumps (back and calf cramps) caused by oral steroids and Clenbuterol. Also provides cardiovascular support.

Half-life: ~1-2 hours (plasma)

Insulin

Never Use

Slin

The single most dangerous compound in bodybuilding. Can kill within minutes through hypoglycaemia. There is no margin for error. This profile exists for awareness, not as a harm reduction pathway.

Half-life: Rapid-acting: ~4-6 hours. Regular: ~6-8 hours.

MK-677 (Ibutamoren)

Never Use

Ibutamoren, Nutrobal

A growth hormone secretagogue that increases GH and IGF-1 levels. NOT a SARM despite being marketed as one. Causes significant hunger and water retention. An oral alternative to injectable HGH.

Half-life: ~24 hours

Cardarine (GW501516)

Never Use

GW501516, Endurobol

A PPAR-delta receptor agonist that enhances endurance. NOT a SARM despite being marketed as one. Abandoned in pharmaceutical trials due to cancer development in rodents. Use carries significant unknown risk.

Half-life: ~16-24 hours

Other Compounds

Modafinil

High Risk

Provigil, Modalert, Modvigil

A wakefulness-promoting agent used off-label for cognitive enhancement. Prescription medication for narcolepsy and sleep disorders. Prohibited in sport on competition days.

Half-life: ~12-15 hours

Ecdysterone

High Risk

Beta-Ecdysterone, 20-Hydroxyecdysone, Turkesterone precursor

A naturally occurring steroid hormone found in insects and some plants. Marketed as a natural anabolic supplement. Evidence for muscle-building effects in humans is limited and controversial.

Half-life: ~8-9 hours

Turkesterone

High Risk

Ajuga Turkestanica extract

A plant-derived ecdysteroid marketed as a natural anabolic. Extremely popular on social media despite very limited scientific evidence for muscle-building effects in humans.

Half-life: Unknown in humans

Laxogenin

High Risk

5a-Hydroxy Laxogenin, 5-Alpha-Hydroxy-Laxogenin

A plant-derived steroidal sapogenin marketed as a natural anabolic. Claims of 200% increase in protein synthesis are not supported by human evidence.

Half-life: Unknown in humans

Chromium Picolinate

High Risk

Chromium

A chromium supplement widely marketed for fat loss, insulin sensitivity, and body composition. Evidence for muscle-building or fat-burning effects is weak.

Half-life: ~24 hours

Berberine

High Risk

Nature's Metformin

A plant alkaloid with glucose-lowering and lipid-modifying effects. Sometimes called 'nature's metformin'. Used for blood sugar management and body composition.

Half-life: ~5-8 hours

Human Growth Hormone (HGH)

Extreme Risk

GH, Somatropin, Growth Hormone

A synthetic version of the naturally occurring growth hormone. Not an anabolic steroid. Promotes fat loss and recovery over months of use. Expensive and commonly counterfeited.

Half-life: ~2-3 hours

Ostarine (MK-2866)

Extreme Risk

MK-2866, Enobosarm, GTx-024

The most widely used SARM. Selectively binds androgen receptors in muscle and bone. Not approved for human use. Suppresses natural testosterone even at low doses.

Half-life: ~24 hours

Ligandrol (LGD-4033)

Extreme Risk

LGD-4033, VK5211, Anabolicum

A potent SARM used for bulking. Produces notable lean mass gains but causes significant testosterone suppression. Not approved for human use.

Half-life: ~24-36 hours

Testolone (RAD-140)

Extreme Risk

RAD-140

One of the most potent SARMs. Produces steroid-like results but also steroid-like suppression. Emerging concerns about neurotoxicity and liver damage. Not approved for human use.

Half-life: ~60 hours

Andarine (S-4)

Extreme Risk

S-4, GTx-007

A SARM known for causing a distinctive yellow tint to vision, particularly at higher doses. Used for cutting. Not approved for human use.

Half-life: ~4-6 hours

Stenabolic (SR-9009)

Extreme Risk

SR-9009

A Rev-ErbA agonist used for endurance and fat loss. NOT a SARM. Has extremely poor oral bioavailability, meaning most of what you swallow does nothing. Often injected or taken sublingually instead.

Half-life: ~4-5 hours

Melanotan-1

Extreme Risk

MT-1, Afamelanotide, Scenesse

A melanocortin receptor agonist used for skin tanning. More selective than Melanotan-2 with fewer sexual side effects. Approved in the EU for erythropoietic protoporphyria but not for cosmetic tanning.

Half-life: ~30 minutes

DMAA

Extreme Risk

1,3-dimethylamylamine, Methylhexaneamine, Geranium Extract

A powerful stimulant formerly found in pre-workout supplements. Banned by the FDA and WADA due to cardiovascular risks including fatal cardiac events.

Half-life: ~8-12 hours

AC-262,356

Extreme Risk

AC-262

An experimental SARM with partial agonist activity at the androgen receptor. Very limited research — even less studied than mainstream SARMs.

Half-life: Unknown — estimated 8-12 hours

ACP-105

Extreme Risk

An experimental SARM developed by Acadia Pharmaceuticals. Similar to AC-262 but with potentially greater potency. Extremely limited research.

Half-life: Unknown — estimated 6-10 hours

LGD-3303

Extreme Risk

A potent SARM developed by Ligand Pharmaceuticals. More potent than LGD-4033 in animal studies but with greater suppressive effects. Never reached human trials.

Half-life: ~6-12 hours

SR-9011

Extreme Risk

A Rev-ErbA agonist similar to SR-9009 (Stenabolic) but with improved oral bioavailability. Used for endurance enhancement and fat loss. Very limited research.

Half-life: ~4-6 hours

Melanotan-2

Never Use

MT-2, Melanotan

A synthetic peptide that stimulates melanin production, causing skin tanning without UV exposure. Linked to melanoma in case reports and not approved for human use anywhere in the world.

Half-life: ~30-60 minutes

SARMs (Selective Androgen Receptor Modulators)

Never Use

Ostarine, MK-2866, Ligandrol, LGD-4033, RAD-140, Testolone

Non-steroidal compounds marketed as a 'safer alternative' to steroids. This framing is largely unsubstantiated. Most were abandoned in clinical trials, long-term safety data is essentially non-existent, and product purity is a major concern.

Half-life: Varies by compound. Ostarine: ~24 hours. LGD-4033: ~24-36 hours. RAD-140: ~16-20 hours.

S-23

Never Use

One of the most potent and suppressive SARMs. Produces near-steroidal results but causes full testosterone shutdown. Was investigated as a male contraceptive. Not approved for human use.

Half-life: ~12 hours

YK-11

Never Use

A steroidal compound marketed as a SARM and myostatin inhibitor. Has a methylated steroid structure making it hepatotoxic. Extremely limited research. Not approved for human use.

Half-life: ~6-10 hours

GW-0742

Never Use

Super Cardarine

A more potent PPARdelta agonist than Cardarine (GW501516). Even less human data. Shares the same cancer concerns as its predecessor. Not approved for human use.

Half-life: ~12-16 hours (estimated)

EPO (Erythropoietin)

Never Use

Erythropoietin, Epoetin alfa, Eprex, Procrit

A hormone that stimulates red blood cell production. Used for endurance enhancement. Dramatically increases blood viscosity, creating serious risk of stroke, heart attack, and death.

Half-life: ~4-13 hours (IV), ~24 hours (subcutaneous)

Synthol

Never Use

Site Enhancement Oil, SEO, Pump N' Pose

An oil injected directly into muscles to increase their visual size. Does not build actual muscle. Causes permanent disfigurement, abscesses, nerve damage, and embolism. Has caused amputations and deaths.

Half-life: N/A — oil persists in muscle tissue indefinitely