Side Effects & Health Risks

Every steroid carries risks. Understanding them does not mean they will not happen to you — it means you can make an informed decision and know what to watch for.

“It won't happen to me” is not a strategy

Every person experiencing serious steroid side effects once believed they would be the exception. Risk is not theoretical — it is statistical. The question is not whether side effects will occur, but which ones and how severely.

Cardiovascular Risks

Cardiovascular damage is the most serious long-term risk of steroid use. It is also the most underappreciated, because the damage is silent — you will not feel your arteries hardening.

Left Ventricular Hypertrophy (LVH)

What happens

The heart is a muscle. Steroids cause it to grow, but unlike skeletal muscle this growth is pathological — the heart walls thicken, reducing its efficiency.

Why it matters

LVH is a major risk factor for heart failure and sudden cardiac death. It can develop within months of use.

What to do

An echocardiogram (heart ultrasound) can detect LVH. If you have used steroids for more than one cycle, consider getting one.

Atherosclerosis

What happens

Steroids accelerate the buildup of plaque in arteries, particularly through their effect on cholesterol (lowering HDL, raising LDL).

Why it matters

This process is largely irreversible. Plaque does not disappear when you stop using. Young men are having heart attacks in their 30s from steroid use.

What to do

Monitor your lipid panel regularly. If your HDL drops below 1.0 mmol/L, this is a significant concern.

Blood Pressure

What happens

Most steroids raise blood pressure through water retention, increased red blood cell mass, or direct vascular effects.

Why it matters

Chronic high blood pressure damages blood vessels, the heart, kidneys, and brain. It is called 'the silent killer' for a reason.

What to do

Buy a home blood pressure monitor. Check regularly. Anything consistently above 140/90 needs addressing.

Polycythaemia (Elevated Red Blood Cells)

What happens

Steroids stimulate red blood cell production. Too many red blood cells make the blood thicker and more likely to clot.

Why it matters

This increases risk of stroke, deep vein thrombosis, and pulmonary embolism.

What to do

Haematocrit should be checked on blood work. Above 54% is concerning. Therapeutic blood donation can help manage this.

Liver Strain

Oral steroids (C17-alpha alkylated compounds) must pass through the liver, placing it under significant strain. Injectable steroids are generally much less hepatotoxic, but not risk-free.

Elevated Liver Enzymes (ALT, AST)

What happens

These enzymes leak into the blood when liver cells are damaged. Oral steroids routinely elevate them.

Why it matters

Mildly elevated enzymes are expected with oral use, but significantly elevated levels (3x+ normal) indicate meaningful liver stress.

What to do

Get liver function tests as part of your blood work. Avoid combining oral steroids with alcohol or paracetamol. Keep oral cycles short (6–8 weeks maximum).

Cholestasis

What happens

A condition where bile flow from the liver is impaired. More common with oral steroids, particularly at higher doses.

Why it matters

Symptoms include jaundice (yellowing skin/eyes), dark urine, pale stools, and severe itching.

What to do

If you notice any of these symptoms, stop the oral compound and see a doctor. This is not something to push through.

Peliosis Hepatis and Liver Tumours

What happens

Rare but documented conditions associated with long-term oral steroid use. Peliosis involves blood-filled cysts in the liver.

Why it matters

These are rare with typical recreational use but the risk increases with prolonged oral cycles.

What to do

Another reason to keep oral cycles short and to get blood work done.

Hormonal Disruption & Fertility

Every steroid cycle disrupts your hormonal system. The longer and heavier the use, the harder recovery becomes. Some users never fully recover natural production.

HPTA Suppression

What happens

Exogenous steroids shut down the hypothalamic-pituitary-testicular axis. Your body stops producing its own testosterone, LH, and FSH.

Why it matters

Recovery after a single moderate cycle is usually possible with proper PCT. After years of use, recovery may be partial or impossible.

What to do

Always have PCT medications on hand before starting a cycle. Get blood work to confirm recovery.

Fertility Impact

What happens

Steroids suppress sperm production. Many users become effectively infertile while on cycle, and some remain so for months or years after stopping.

Why it matters

If you want children in the future, this is a serious consideration. HCG during cycle can help maintain some testicular function, but it is not guaranteed.

What to do

Consider a semen analysis before your first cycle if fertility matters to you. Consider sperm banking.

Testicular Atrophy

What happens

Without stimulation from LH, the testes shrink during steroid use.

Why it matters

Usually reversible with PCT, but prolonged use can lead to permanent reduction in testicular size and function.

What to do

HCG during cycle can help maintain testicular size and function, making PCT recovery easier.

Gynecomastia

The development of breast tissue in men, caused by elevated oestrogen levels from aromatising steroids. Once the tissue has formed, only surgery can remove it.

How it develops

What happens

Testosterone and other steroids can convert (aromatise) to oestrogen. Elevated oestrogen stimulates breast tissue growth.

Why it matters

Early signs include nipple sensitivity, itching, and small lumps behind the nipple. If caught early, it may be reversible with SERMs. If tissue has solidified, surgery is the only option.

What to do

Monitor nipple sensitivity. Have an aromatase inhibitor (AI) on hand. Do not let it progress — early intervention is key. But also do not crash your oestrogen with excessive AI use, as low oestrogen carries its own serious side effects.

Psychological Effects

The psychological effects of steroids are often underestimated. They affect mood, behaviour, and mental health — and you are often the last person to notice the changes in yourself.

Mood and Behavioural Changes

What happens

Steroids can cause irritability, aggression, anxiety, and mood swings. These are not just anecdotal — they are documented hormonal effects.

Why it matters

The people around you will notice before you do. Relationship damage, workplace issues, and social isolation are common.

What to do

Ask someone you trust to be honest with you about changes in your behaviour. If multiple people are telling you something has changed, listen.

Depression (Particularly Post-Cycle)

What happens

The crash in testosterone after a cycle, combined with elevated oestrogen, frequently causes depression. This is biochemical, not weakness.

Why it matters

Post-cycle depression is one of the most dangerous periods. It drives many users back onto steroids and is associated with suicidal ideation.

What to do

Know that this is coming and plan for it. Tell someone you trust. Have your GP's number ready. If you experience suicidal thoughts, call Samaritans on 116 123.

Body Dysmorphia and Dependency

What happens

Steroids can worsen or create body dysmorphic disorder. You may never feel big enough, lean enough, or good enough. This drives continued and escalating use.

Why it matters

This is one of the least discussed but most significant risks. Many users describe being unable to stop despite wanting to, because they cannot tolerate how they look or feel without steroids.

What to do

If you are unable to take a break from steroids, or if the thought of being smaller causes you significant distress, consider speaking to a mental health professional.

Hair Loss & Acne

These are among the most visible and most common side effects. For many users, they are also the most distressing.

Male Pattern Hair Loss

What happens

Steroids accelerate genetic hair loss through increased DHT (dihydrotestosterone) activity. If you are genetically predisposed to hair loss, steroids will speed it up — sometimes dramatically.

Why it matters

This is dose-dependent and compound-dependent (some compounds are worse than others). The damage is not always reversible.

What to do

If hair matters to you, research the androgenic rating of compounds before using them. Finasteride can help but carries its own side effects and does not work with all compounds.

Acne

What happens

Hormonal fluctuations from steroids cause increased sebum production, leading to acne — often severe and typically on the back, shoulders, and face.

Why it matters

Can be severe enough to cause scarring. Often worsens when coming off cycle due to hormonal instability.

What to do

Keep skin clean. If severe, a GP can prescribe treatments. Accutane (isotretinoin) is sometimes used but has significant side effects of its own.

Risks of Starting Young

If you are under 25, and especially if you are under 18, the risks of steroid use are significantly higher than for older adults. This is not a scare tactic — it is biology.

Growth Plate Closure

What happens

Before around age 18–21, your bones are still growing. Elevated androgen levels can cause the growth plates to fuse prematurely.

Why it matters

This means steroids can permanently stunt your height. The irony of using steroids to look better while potentially making yourself shorter is lost on many young users.

What to do

If you have not finished growing, do not use anabolic steroids. This is one of the few genuinely irreversible consequences.

Brain Development

What happens

The prefrontal cortex — responsible for decision-making, impulse control, and emotional regulation — continues developing until approximately age 25.

Why it matters

Introducing supraphysiological hormones during this period can affect neurological development. The psychological side effects (mood, aggression, impulsivity) may be more severe in younger users.

What to do

Waiting until at least 25 is the most commonly cited harm reduction recommendation, and it exists for a reason.

Hormonal Development

What happens

Your hormonal system is still developing through your early 20s. Disrupting it during this period risks more lasting damage than disrupting it as a mature adult.

Why it matters

Recovery from HPTA suppression is harder when the system was never fully established in the first place.

What to do

If you are under 25, you are also at your peak natural testosterone. You have more to work with naturally than you think. Get blood work to confirm your baseline before making a decision.

Online Influence & Mental Health

The psychological risks of steroids do not exist in a vacuum. For many young men, the decision to use is shaped by online communities that exploit insecurity and normalise escalating behaviour. Understanding this pipeline is part of understanding the risks.

Blackpill & Looksmaxing

What it is

Looksmaxing communities promote steroids as tools for achieving a more masculine appearance — claiming testosterone will reshape your jawline, HGH will change your facial bone structure, and a bigger body will fix your confidence. These claims are overwhelmingly exaggerated. In adults, exogenous testosterone does not cause meaningful skeletal changes. HGH abuse causes acromegaly, not attractiveness.

Why it matters

The blackpill ideology validates real pain — loneliness, social struggle, unhappiness with appearance — but then traps people in hopelessness while simultaneously selling them solutions. The contradiction is the business model: make people feel broken, then sell them fixes.

What to watch for

Content creators who make you feel worse about yourself before offering a product. Before/after transformations that do not disclose lighting, angles, or drug use. Anyone who frames disagreement as “cope” — a thought-terminating cliché designed to prevent critical thinking.

The Pipeline to Extremism

What happens

The pathway typically follows four stages: self-improvement content (fitness, grooming) → masculinity content (what it means to be a man) → grievance content (why life is unfair) → ideological content (who is to blame). Algorithms accelerate this because emotional content drives engagement.

Why it matters

Steroid use often sits at the intersection of self-improvement and grievance content. The same communities that normalise steroid use also promote increasingly extreme worldviews. Social disengagement, anger, and isolation are both causes and consequences.

What to watch for

Us-vs-them framing. Escalating anger at groups of people. Thought-terminating clichés. Conspiracy thinking. Content that isolates you from people who care about you. If you are concerned, Exit UK and ACT Early provide confidential support.

Who Profits

What happens

Most content creators in these spaces are running a business. Their revenue comes from views, affiliate links, supplement sales, coaching packages, and course enrolments. Your insecurity is monetised. Despair is profitable.

The test

Ask yourself whether the content you are consuming makes you feel more capable and informed, or more hopeless and dependent. Useful information empowers you. Exploitative content traps you.

Blood work is how you see what you cannot feel

Most of the serious risks on this page — cardiovascular damage, liver strain, hormonal disruption — can be detected through blood tests before they become symptomatic. Get tested.

Read the Blood Work Guide

If you are struggling with your mental health

Post-cycle depression is real and it can be severe. If you are having suicidal thoughts, please reach out.

Samaritans: 116 123CALM: 0800 58 58 58Text SHOUT to 85258